| Clyatt | Coachman | Cobb | Cobia | Cocheran | Cochran | Cochron |
| Cocke | Cockram | Cockran | Cockrun | Coday | Codding | Coe |
| Coenis | Coffee | Coffer | Coffey | Cofield | Cohen | Coker |
| Colbert | Colburn | Cole | Coleman | Coleson | Colier | Colins |
| Colious | Colk | Collar | Coller | Collier | Collin | Collins |
| Colly | Colman | Colson | Colter | Colteryahn | Colton | Colvin |
| Colwell | Colyer | Combe | Combee | Compsie | Compton | Conahadjo |
| Conaway | Cone | Conell | Congdon | Coniers | Conley | Conliff |
| Connel | Connell | Connelly | Conner | Conniers | Connolly | Connoly |
| Connor | Connors | Conolly | Conrad | Conroy | Consoe | Constantine |
| Conway | Conyer | Conyers | Coody | Cook | Cooke | Cooley |
| Cooly | Coon | Cooney | Coons | Cooper | Copeland | Copelin |
| Coplin | Coppernoll | Coram | Corbett | Corbin | Corbitt | Corbon |
| Cordell | Cordery | Core | Corey | Corley | Cornall | Corneilus |
| Cornelison | Cornelius | Corner | Corney | Cornpatch | Cornwell | Corpie |
| Corpin | Corrigan | Corson | Cortello | Costine | Coston | Cothern |
| Cothran | Cottingham | Cottle | Cotton | Cottrell | Couch | Coulter |
| Council | Courtney | Covacevich | Cover | Covington | Cowan | Coward |
| Cowart | Cowder | Cowdery | Cowen | Cower | Cox | Coxwell |
| Coyle | Crabtree | Craft | Craid | Craig | Cram | Cramer |
| Crane | Craneer | Cranford | Crass | Craw | Crawford | Crawley |
| Crawson | Cray | cre | Creamer | Creed | Creel | Creig |
| Creighton | Crely | Cremer | Crenshaw | Crews | Crews Jr | Cribb |
| Cribbs | Crichton | Crig | Crine | Crippen | Crisman | Criss |
| Criswell | Crittenden | Crobitt | Crockett | Crofford | Croft | Croker |
| Cromartie | Cronan | Crooker | Croom | Crosby | Crosier | Cross |
| Crosson | Crow | Crowder | Crowley | Croyol | Crozier | Crue |
| Cruise | Crum | Crumpton | Cruse | Crutcher | Cruzado | Culbreath |
| Cullinaine | Cumbee | Cummhan | Cumming | Cummings | Cummins | Cundiff |
| Cuney | Cunliff | Cunliffe | Cunlisk | Cunnigham | Cunningham | Cunny |
| Curley | Curnick | Currey | Currie | Currier | Curry | Curtis |
| Cushing | Cusker | Custer | Cuthbert | Cuthcart | Cutshall | Cutts |
| D | D H A | Dabney | Daegenhart | Dagenhart | Daigneau | Dailey |
| Dalanny | Dallas | Dalton | Daly | Dambury | Damn | Dampier |
| Dana | Dancy | Danels | Danford | Danham | Daniel | Daniels |
| Danielson | Danks | Danley | Dann | Danniels | Dantzler | Darby |
| Dardis | Dargan | Darling | Darna | Darry | Dartey | Darton |
| Dashut | Dassex | Daugherty | Daughter | Daughtery | Daughtrey | Daughtry |
| Daukens | DaVault | Davenport | Davice | David | Davidson | Davie |
| Davies | Davis | Davison | Davit | Davs | Dawson | Day |
| Days | Dazey | De ? | De St Croix | dea | Deadwyler | Dealy |
| Dean | Deas | Deason | DeBusque | Decaster | DeCosta | DeCostas |
| DeCoste | DeCoster | Decostes | Dees | Deese | Deeson | Defonfridr |
| DeFougeris | Deis | Deitrick | Delaney | Delano | Delany | Delauaney |
| DeLaunau | DeLaunay | DeLauney | Delespin | Delgado | DeLifus | Dell |
| DeLoach | DeLounay | DeMaster | DeMasters | Deming | Denham | Denison |
| Denling | Dennie | Dennis | Dennison | Denny | Densten | Denton |
| DeOca | Depisc | Deppster | Depuy | Derbley | Derby | Derieux |
| Derr | DeRussey | DeRussey, | DeRussy | Desforges | DeShanix | DeShong |
| Desiderio | Deson | DeTarr | Deutsch | Devain | Devall | DeVane |
| Devans | Deveneau | Devenport | DeVille | Devine | DeVore | DeVries |
| Dew | Dewett | Dewey | Dewit | Dewitt | Dexter | DeYoung |
| Dias | Dick | Dickens | Dickenson | Dickerson | Dickey | Dickhut |
| Dickie | Dickinson, | Dickson | Dider | Didier | Didman | Diggs |
| Dikes | Dileherial | Dill | Dillard | Dillinger | Dillon | Dime |
| Dimick | Diming | Dimsdale | Dishong | Dityens | Ditzel | Divine |
| Dixon | Doane | Dobbins | Dobson | Doctor | Dodd | Dodgen |
| Dodson | Doehling | Dollohide | Dolly | Donald | Donaldson | Donalson |
| Donathan | Donnmeek | Donovan | Dooley | Doolin | Dorman | Dormany |
| Dorminey | Dorson | Dortch | Dorwin | Dossey | Dossy | Dotson |
| Doty | Doughdy | Dougherty | Doughlas | Doughtery | Douglas | Douglass |
| Douless | Douling | Dove | Dover | Dow | Dowdle | Dowless |
| Dowling | Downing | Downs | Doxsee | Doyle | Dozier | Drake |
| Drane | Draper | Drawdy | Dreggers | Dreggors | Drelighn | Drew |
| Drewry | Driggers | Driscoll | Drown | Dryman | DuBarry | Dubise |
| Dubois | Dubose | Duckwall | Duckworth | Dudley | Duffel | Duffell |